A Randomized Study of Chemotherapy Versus Biochemotherapy with Chemotherapy plus Aloe arborescens in Patients with Metastatic Cancer - ( PubMed doc )


PAOLO LISSONI, FRANCO ROVELLI, FERNANDO BRIVIO, ROMANO ZAGO, MASSIMO COLCIAGO, GIUSEPPINA MESSINA, ADELIO MORA and GIORGIO PORRO

Division of Radiation Oncology, Division of Surgery, St. Gerardo Hospital, Monza, Milan; Aloe Foundation, Isernia; I.N.R.C.A Laboratory of Analysis, Lecco, Italy

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Aloe is one of the of the most important plants exhibiting anticancer activity and its antineoplastic property
PMID: 19368145 [PubMed - indexed for MEDLINE]

The recent advances in the analysis of tumor immunobiology suggest the possibility of biologically manipulating the efficacy and toxicity of cancer chemotherapy by endogenous or exogenous immunomodulating substances. Aloe is one of the of the most important plants exhibiting anticancer activity and its antineoplastic property is due to at least three different mechanisms, based on antiproliferative, immunostimulatory and antioxidant effects. The antiproliferative action is determined by anthracenic and antraquinonic molecules, while the immunostimulating activity is mainly due to acemannan.
RESULT: The percentage of both objective tumor regressions and disease control was significantly higher in patients concomitantly treated with Aloe than with chemotherapy alone, as well as the percent of 3-year survival patients.
Aloe in chemotherapy.pdf
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Dietary Aloe Improves Insulin Sensitivity via the Suppression of Obesity-induced Inflammation in Obese Mice
DOI 10.4110/in.2011.11.1.59
Background: Insulin resistance is an integral feature of metabolic syndromes, including obesity, hyperglycemia, and hyperlipidemia. In this study, we evaluated whether the aloe component could reduce obesity-induced inflammation and
the occurrence of metabolic disorders such as blood glucose and insulin resistance.
aloe_obesity.pdf
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Aloe Vera (Av) gel with its multiple beneficial effects.
DOI: 10.5897/JMPR12.333
A. vera (Av) gel has about 75 active constituents which are largely classified into alkaloids, glycoproteins, resins, enzymes, vitamins, amino acids, minerals, salicylic acids, sterols, genolins, saponis, lignin and polysaccharides.
(Atherton, 1998; Holanda et al., 2009; Ni et al., 2004).
Journal of Medicinal Plants Research.pdf
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Inhibition of tumor angiogenesis by cannabinoids
0892-6638/03/0017-0529
Cannabinoids, the active components of marijuana and their derivatives, inhibit tumor growth in animal models, but the mechanism of their anti-tumoral action in
vivo is still unclear. Because the generation of a new vascular supply (angiogenesis) is causally involved in the progression of the majority of solid tumors, the aim of this study was to test whether cannabinoids inhibit
tumor angiogenesis.
Inhibition of tumor angiogenesis by cann
Documento Adobe Acrobat 218.2 KB